Post-Translational Modification Analysis of VDAC1 in ALS-SOD1 Model Cells Reveals Specific Asparagine and Glutamine Deamidation

Mitochondria from affected tissues of amyotrophic lateral sclerosis (ALS) patients show morphological and biochemical abnormalities. Mitochondrial dysfunction causes oxidative damage and the accumulation of ROS, and represents one of the major triggers of selective death of motor neurons in ALS. We...

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Detalles Bibliográficos
Autores principales: Pittalà, Maria Gaetana Giovanna, Reina, Simona, Cubisino, Salvatore Antonio Maria, Cucina, Annamaria, Formicola, Beatrice, Cunsolo, Vincenzo, Foti, Salvatore, Saletti, Rosaria, Messina, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761621/
https://www.ncbi.nlm.nih.gov/pubmed/33276691
http://dx.doi.org/10.3390/antiox9121218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761621/
https://www.ncbi.nlm.nih.gov/pubmed/33276691
http://dx.doi.org/10.3390/antiox9121218

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