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Five Italian Families with Two Mutations in BRCA Genes

Double heterozygosity (DH) in BRCA1 and BRCA2 genes and double mutation (DM) in BRCA1 or BRCA2 are extremely rare events in the general population, and few cases have been reported worldwide so far. Here, we describe five probands, all women, with breast and/or ovarian cancer and their families. Par...

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Detalles Bibliográficos
Autores principales:	Vietri, Maria Teresa, Caliendo, Gemma, D’Elia, Giovanna, Resse, Marianna, Casamassimi, Amelia, Minucci, Pellegrino Biagio, Dello Ioio, Concetta, Cioffi, Michele, Molinari, Anna Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761639/ https://www.ncbi.nlm.nih.gov/pubmed/33287145 http://dx.doi.org/10.3390/genes11121451

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