A Tangle of Genomic Aberrations Drives Multiple Myeloma and Correlates with Clinical Aggressiveness of the Disease: A Comprehensive Review from a Biological Perspective to Clinical Trial Results

Multiple myeloma (MM) is a genetically heterogeneous disease, in which the process of tumorigenesis begins and progresses through the appearance and accumulation of a tangle of genomic aberrations. Several are the mechanisms of DNA damage in MM, varying from single nucleotide substitutions to comple...

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Detalles Bibliográficos
Autores principales: Sessa, Mariarosaria, Cavazzini, Francesco, Cavallari, Maurizio, Rigolin, Gian Matteo, Cuneo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761770/
https://www.ncbi.nlm.nih.gov/pubmed/33287156
http://dx.doi.org/10.3390/genes11121453

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