Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC, also known as pancreatic cancer) is one of the deadliest tumor types, characterized by poor prognosis, profound chemoresistance and overall low survival. Gemcitabine remains the standard of care for all stages of PDAC, however, with poor clinic...

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Detalles Bibliográficos
Autores principales: Amrutkar, Manoj, Vethe, Nils Tore, Verbeke, Caroline S., Aasrum, Monica, Finstadsveen, Anette Vefferstad, Sántha, Petra, Gladhaug, Ivar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761836/
https://www.ncbi.nlm.nih.gov/pubmed/33287390
http://dx.doi.org/10.3390/cancers12123628

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