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Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus

Norovirus outbreaks frequently occur in closed or semiclosed institutions. Recent studies in Catalonia and various countries indicate that, during outbreaks in these institutions, norovirus is detected in between 23% and 60% of workers, and the prevalence of infection in asymptomatic workers involve...

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Autores principales: Parrón, Ignacio, Barrabeig, Irene, Alseda, Miquel, Cornejo-Sánchez, Thais, Guix, Susana, Jané, Mireia, Izquierdo, Conchita, Rius, Cristina, Domínguez, Àngela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762007/
https://www.ncbi.nlm.nih.gov/pubmed/33291823
http://dx.doi.org/10.3390/v12121392
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author Parrón, Ignacio
Barrabeig, Irene
Alseda, Miquel
Cornejo-Sánchez, Thais
Guix, Susana
Jané, Mireia
Izquierdo, Conchita
Rius, Cristina
Domínguez, Àngela
author_facet Parrón, Ignacio
Barrabeig, Irene
Alseda, Miquel
Cornejo-Sánchez, Thais
Guix, Susana
Jané, Mireia
Izquierdo, Conchita
Rius, Cristina
Domínguez, Àngela
author_sort Parrón, Ignacio
collection PubMed
description Norovirus outbreaks frequently occur in closed or semiclosed institutions. Recent studies in Catalonia and various countries indicate that, during outbreaks in these institutions, norovirus is detected in between 23% and 60% of workers, and the prevalence of infection in asymptomatic workers involved in outbreaks ranges from 17% to 40%. In this work, we carried out a prospective study to investigate the involvement of workers in closed and semiclosed institutions during outbreaks. The attack rates (ARs) and the rate ratios (RRs) were calculated according to the type of transmission and occupational category. The RRs and 95% confidence intervals (CIs) between workers and users were calculated. The mean cycle of quantification (Cq) values were compared according to the genogroup and the presence of symptoms. ARs were higher in person-to-person transmission than in common vehicle outbreaks, and 38.8% of workers were symptomatic. The RR between workers and users was 0.46 (95% CI 0.41–0.52). The ARs in workers were high, particularly in workers with closer contact with users. The mean Cq was lower in patients than in asymptomatic infected persons, although the difference was only significant for genogroup I (GI). The frequency of asymptomatic infected persons suggests that personal hygiene measures should be followed by all workers in the centers affected.
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spelling pubmed-77620072020-12-26 Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus Parrón, Ignacio Barrabeig, Irene Alseda, Miquel Cornejo-Sánchez, Thais Guix, Susana Jané, Mireia Izquierdo, Conchita Rius, Cristina Domínguez, Àngela Viruses Article Norovirus outbreaks frequently occur in closed or semiclosed institutions. Recent studies in Catalonia and various countries indicate that, during outbreaks in these institutions, norovirus is detected in between 23% and 60% of workers, and the prevalence of infection in asymptomatic workers involved in outbreaks ranges from 17% to 40%. In this work, we carried out a prospective study to investigate the involvement of workers in closed and semiclosed institutions during outbreaks. The attack rates (ARs) and the rate ratios (RRs) were calculated according to the type of transmission and occupational category. The RRs and 95% confidence intervals (CIs) between workers and users were calculated. The mean cycle of quantification (Cq) values were compared according to the genogroup and the presence of symptoms. ARs were higher in person-to-person transmission than in common vehicle outbreaks, and 38.8% of workers were symptomatic. The RR between workers and users was 0.46 (95% CI 0.41–0.52). The ARs in workers were high, particularly in workers with closer contact with users. The mean Cq was lower in patients than in asymptomatic infected persons, although the difference was only significant for genogroup I (GI). The frequency of asymptomatic infected persons suggests that personal hygiene measures should be followed by all workers in the centers affected. MDPI 2020-12-04 /pmc/articles/PMC7762007/ /pubmed/33291823 http://dx.doi.org/10.3390/v12121392 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Parrón, Ignacio
Barrabeig, Irene
Alseda, Miquel
Cornejo-Sánchez, Thais
Guix, Susana
Jané, Mireia
Izquierdo, Conchita
Rius, Cristina
Domínguez, Àngela
Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus
title Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus
title_full Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus
title_fullStr Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus
title_full_unstemmed Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus
title_short Involvement of Workers in Closed and Semiclosed Institutions in Outbreaks of Acute Gastroenteritis Due to Norovirus
title_sort involvement of workers in closed and semiclosed institutions in outbreaks of acute gastroenteritis due to norovirus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762007/
https://www.ncbi.nlm.nih.gov/pubmed/33291823
http://dx.doi.org/10.3390/v12121392
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