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DDB2 Genetic Risk Factor for Ocular Squamous Cell Carcinoma Identified in Three Additional Horse Breeds

Squamous cell carcinoma (SCC) is the most common cancer affecting the equine eye. A missense variant within the gene damage-specific DNA binding protein 2 (DDB2 c.1013C>T, p.Thr338Met) was previously identified as a causal recessive genetic risk factor for the development of ocular SCC within Haf...

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Detalles Bibliográficos
Autores principales: Crausaz, Margo, Launois, Thomas, Smith-Fleming, Kathryn, McCoy, Annette M., Knickelbein, Kelly E., Bellone, Rebecca R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762027/
https://www.ncbi.nlm.nih.gov/pubmed/33291392
http://dx.doi.org/10.3390/genes11121460