Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization

Sulpiride (SUL) is a dopamine D(2)-receptor antagonist used for management of GIT disturbance and it has anti-psychotic activities based on the administered dose. SUL undergoes P-glycoprotein efflux, which lead to poor bioavailability and erratic absorption. Therefore, the objective of this research...

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Detalles Bibliográficos
Autores principales: M. Tawfeek, Hesham, Hassan, Yasser A., Aldawsari, Mohammed F., H. Fayed, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762047/
https://www.ncbi.nlm.nih.gov/pubmed/33291402
http://dx.doi.org/10.3390/ph13120446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762047/
https://www.ncbi.nlm.nih.gov/pubmed/33291402
http://dx.doi.org/10.3390/ph13120446

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