New Insights into the Binding Features of F508del CFTR Potentiators: A Molecular Docking, Pharmacophore Mapping and QSAR Analysis Approach

Cystic fibrosis (CF) is the autosomal recessive disorder most recurrent in Caucasian populations. To combat this disease, many life-prolonging therapies are required and deeply investigated, including the development of the so-called cystic fibrosis transmembrane conductance regulator (CFTR) modulat...

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Detalles Bibliográficos
Autores principales: Righetti, Giada, Casale, Monica, Tonelli, Michele, Liessi, Nara, Fossa, Paola, Pedemonte, Nicoletta, Millo, Enrico, Cichero, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762081/
https://www.ncbi.nlm.nih.gov/pubmed/33291847
http://dx.doi.org/10.3390/ph13120445

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