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NEK1 Phosphorylation of YAP Promotes Its Stabilization and Transcriptional Output

SIMPLE SUMMARY: We earlier described the involvement of the TLK1>NEK1>ATR>Chk1 axis as a key determinant of cell cycle arrest in androgen-dependent prostate cancer (PCa) cells after androgen deprivation. We now report that the TLK1>NEK1 axis is also involved in stabilization of yes-assoc...

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Detalles Bibliográficos
Autores principales: Khalil, Md Imtiaz, Ghosh, Ishita, Singh, Vibha, Chen, Jing, Zhu, Haining, De Benedetti, Arrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762262/
https://www.ncbi.nlm.nih.gov/pubmed/33297404
http://dx.doi.org/10.3390/cancers12123666

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