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Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial monotopic membrane protein that plays an essential role in the pyrimidine de novo biosynthesis and electron transport chain pathways. In Eimeria tenella, an intracellular apicomplexan parasite that causes the most severe form of chicken coccidi...

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Detalles Bibliográficos
Autores principales: Sato, Dan, Hartuti, Endah Dwi, Inaoka, Daniel Ken, Sakura, Takaya, Amalia, Eri, Nagahama, Madoka, Yoshioka, Yukina, Tsuji, Naotoshi, Nozaki, Tomoyoshi, Kita, Kiyoshi, Harada, Shigeharu, Matsubayashi, Makoto, Shiba, Tomoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762340/
https://www.ncbi.nlm.nih.gov/pubmed/33297567
http://dx.doi.org/10.3390/genes11121468