Cargando…

Inhibition of SARS-CoV-2 Entry into Host Cells Using Small Molecules

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a virus belonging to the Coronavirus family, is now known to cause Coronavirus Disease (Covid-19) which was first recognized in December 2019. Covid-19 leads to respiratory illnesses ranging from mild infections to pneumonia and lung fail...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al Adem, Kenana, Shanti, Aya, Stefanini, Cesare, Lee, Sungmun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762362/ https://www.ncbi.nlm.nih.gov/pubmed/33302344 http://dx.doi.org/10.3390/ph13120447

Ejemplares similares

Hydrogen phosphate selectively induces MDA MB 231 triple negative breast cancer cell death in vitro
por: Shanti, Aya, et al.
Publicado: (2022)

Linking Alzheimer’s Disease and Type 2 Diabetes: Characterization and Inhibition of Cytotoxic Aβ and IAPP Hetero-Aggregates
por: Al Adem, Kenana, et al.
Publicado: (2022)

Structural polymorphism and cytotoxicity of brain‐derived β‐amyloid extracts
por: Al Adem, Kenana, et al.
Publicado: (2023)

In Silico Screening and Testing of FDA-Approved Small Molecules to Block SARS-CoV-2 Entry to the Host Cell by Inhibiting Spike Protein Cleavage
por: Ozdemir, E. Sila, et al.
Publicado: (2022)

SARS-CoV-2 Entry Inhibitors: Small Molecules and Peptides Targeting Virus or Host Cells
por: Cannalire, Rolando, et al.
Publicado: (2020)

Identification of potent small molecule inhibitors of SARS-CoV-2 entry
por: Mediouni, Sonia, et al.
Publicado: (2022)

Role of host factors in SARS-CoV-2 entry
por: Evans, John P., et al.
Publicado: (2021)

Roles of host proteases in the entry of SARS-CoV-2
por: Zabiegala, Alexandria, et al.
Publicado: (2023)

Aggregation and Cellular Toxicity of Pathogenic or Non-pathogenic Proteins
por: Lee, Sungmun, et al.
Publicado: (2020)

Existence of SARS-CoV-2 Entry Molecules in the Oral Cavity
por: Sakaguchi, Wakako, et al.
Publicado: (2020)

Targeting the GRP78-Dependant SARS-CoV-2 Cell Entry by Peptides and Small Molecules
por: Allam, Loubna, et al.
Publicado: (2020)

Multi-Compartment Lymph-Node-on-a-Chip Enables Measurement of Immune Cell Motility in Response to Drugs
por: Hallfors, Nicholas, et al.
Publicado: (2021)

Effect of Exogenous pH on Cell Growth of Breast Cancer Cells
por: Lee, Sungmun, et al.
Publicado: (2021)

pH profiles of 3-chymotrypsin-like protease (3CLpro) from SARS-CoV-2 elucidate its catalytic mechanism and a histidine residue critical for activity
por: Al Adem, Kenana, et al.
Publicado: (2022)

Discovery of Small Molecule Entry Inhibitors Targeting the Fusion Peptide of SARS-CoV-2 Spike Protein
por: Hu, Xin, et al.
Publicado: (2021)

Nanocomposite Conductive Bioinks Based on Low-Concentration GelMA and MXene Nanosheets/Gold Nanoparticles Providing Enhanced Printability of Functional Skeletal Muscle Tissues
por: Boularaoui, Selwa, et al.
Publicado: (2021)

Structural understanding of SARS-CoV-2 virus entry to host cells
por: Le, Kim, et al.
Publicado: (2023)

New Phenolic Lipids from the Leaves of Clausena harmandiana Inhibit SARS-CoV-2 Entry into Host Cells
por: Chambon, Marion, et al.
Publicado: (2023)

Hydroxychloroquine: mechanism of action inhibiting SARS-CoV2 entry.
por: Yuan, Zixuan, et al.
Publicado: (2020)

Three-Dimensional Visualization of Viral Structure, Entry, and Replication Underlying the Spread of SARS-CoV-2
por: Saville, James W., et al.
Publicado: (2022)

Inhibition of Human Cytomegalovirus Entry into Host Cells through A Pleiotropic Small Molecule
por: Elste, James, et al.
Publicado: (2020)

Does a host restriction factor facilitate entry of SARS-CoV-2?
por: Gea-Mallorquí, Ester
Publicado: (2020)

A potential role for integrins in host cell entry by SARS-CoV-2
por: Sigrist, Christian JA, et al.
Publicado: (2020)

Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells
por: Millet, Jean Kaoru, et al.
Publicado: (2018)

SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention
por: Mahmoud, Ismail Sami, et al.
Publicado: (2020)

Cell entry by SARS-CoV-2
por: Peng, Ruchao, et al.
Publicado: (2021)

Clotting and SARS-CoV-2 entry
por: Hofer, Ursula
Publicado: (2022)

Evaluation of the Cytotoxic and Antiviral Effects of Small Molecules Selected by In Silico Studies as Inhibitors of SARS-CoV-2 Cell Entry
por: Carvalhal, Francisca, et al.
Publicado: (2023)

Kidney injury molecule-1: a novel entry factor for SARS-CoV-2
por: Wan, Cheng, et al.
Publicado: (2021)

Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
por: Tandon, Ritesh, et al.
Publicado: (2020)

Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry
por: Guseman, Alex J., et al.
Publicado: (2022)

LRRC15 inhibits SARS-CoV-2 cellular entry in trans
por: Song, Jaewon, et al.
Publicado: (2022)

Targeting spike glycans to inhibit SARS-CoV2 viral entry
por: Guseman, Alex J., et al.
Publicado: (2023)

Spike Glycoprotein and Host Cell Determinants of SARS-CoV-2 Entry and Cytopathic Effects
por: Nguyen, Hanh T., et al.
Publicado: (2021)

SARS-CoV-2 Spike-Mediated Entry and Its Regulation by Host Innate Immunity
por: Yu, Shi, et al.
Publicado: (2023)

Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels
por: Cecon, Erika, et al.
Publicado: (2022)

Cell entry mechanisms of SARS-CoV-2
por: Shang, Jian, et al.
Publicado: (2020)

SARS-CoV-2, Early Entry Events
por: Chambers, James P., et al.
Publicado: (2020)

Mechanisms of SARS-CoV-2 entry into cells
por: Jackson, Cody B., et al.
Publicado: (2021)

In Vitro Immune Organs-on-Chip for Drug Development: A Review
por: Shanti, Aya, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kthfb5ar42u4i9dl18e36nlm70