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Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines
Sorafenib has long been the only approved systemic therapy for advanced hepatocellular carcinoma (HCC), but most patients show primary or acquired drug resistance. In the present study, RNA was extracted from sorafenib-resistant and -sensitive clones of the HCC cell lines HepG2 and Huh7. Protein-pro...
Autores principales: | Zhang, Zhi, He, Cheng-Zu, Qin, Ya-Qin, Liao, Jian-Jun, Huang, Shang-Tao, Mo, Steven, Li, Hong-Mian, Lin, Jian-Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762478/ https://www.ncbi.nlm.nih.gov/pubmed/33234725 http://dx.doi.org/10.18632/aging.104195 |
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