TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy

Autophagy is involved in degenerative diseases such as osteoarthritis and disc degeneration. Although, tumor necrosis factor α-induced protein 3 (TNFAIP3) is well-known as a key regulator of inflammation and autophagy, it is still not clear whether TNFAIP3 regulates autophagy to protect from human d...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Ma, Yufei, Yang, Zhijie, Lan, Haiyang, Liu, Guangliang, Zhang, Ye, Xia, Huiqiang, Wang, Xiaofang, Han, Fei, Tu, Xiaolin, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762495/
https://www.ncbi.nlm.nih.gov/pubmed/33226960
http://dx.doi.org/10.18632/aging.104160

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