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E3 ligase FBXW7 restricts M2-like tumor-associated macrophage polarization by targeting c-Myc

FBXW7 functions as an E3 ubiquitin ligase to mediate oncoprotein degradation via the ubiquitin-proteasome system in cancer cells, effectively inhibiting the growth and survival of tumor cells. However, little is known about the functions of FBXW7 in macrophages and the tumor immune microenvironment....

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Detalles Bibliográficos
Autores principales:	Zhong, Lijia, Zhang, Yuanyuan, Li, Mengyao, Song, Yinjing, Liu, Danhui, Yang, Xin, Yang, Dehua, Qu, Hao, Lai, Lihua, Wang, Qingqing, Chen, Zhimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762499/ https://www.ncbi.nlm.nih.gov/pubmed/33260160 http://dx.doi.org/10.18632/aging.202293

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