Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway

Ischemia/reperfusion (I/R) injury is a life-threatening vascular emergency following myocardial infarction. Our previous study showed cardioprotective effects of metformin against myocardial I/R injury. In this study, we further examined the involvement of AMPK mediated activation of NLRP3 inflammas...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Huang, Lelin, Shi, Xing, Yang, Liu, Hua, Fuzhou, Ma, Jianyong, Zhu, Wengen, Liu, Xiao, Xuan, Rui, Shen, Yunfeng, Liu, Jianping, Lai, Xiaoyang, Yu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762510/
https://www.ncbi.nlm.nih.gov/pubmed/33232283
http://dx.doi.org/10.18632/aging.202143

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