The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats

A better understanding of the impact of molecular size and linkers is important for PEG-based hyperbranched polymers (HBPs) intended as tailored drug delivery vehicles. This study aimed to evaluate the effects of crosslinker chemistry (cleavable disulphide versus non-cleavable ethylene glycol methac...

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Detalles Bibliográficos
Autores principales: Marasini, Nirmal, Fu, Changkui, Fletcher, Nicholas L., Subasic, Christopher, Er, Gerald, Mardon, Karine, Thurecht, Kristofer J., Whittaker, Andrew K., Kaminskas, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762536/
https://www.ncbi.nlm.nih.gov/pubmed/33302413
http://dx.doi.org/10.3390/nano10122452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762536/
https://www.ncbi.nlm.nih.gov/pubmed/33302413
http://dx.doi.org/10.3390/nano10122452

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