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Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach

SIMPLE SUMMARY: We applied the genomic fabric principles for personalized gene therapy to a case of clear cell renal cell carcinoma (ccRCC). Despite decades of research, the process of finding the molecular mechanisms responsible for the disease and, more importantly, the therapeutic solution is sti...

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Detalles Bibliográficos
Autores principales: Iacobas, Dumitru A., Mgbemena, Victoria E., Iacobas, Sanda, Menezes, Kareena M., Wang, Huichen, Saganti, Premkumar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762545/
https://www.ncbi.nlm.nih.gov/pubmed/33302383
http://dx.doi.org/10.3390/cancers12123678