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The Role of Copper (II) on Kininogen Binding to Tropomyosin in the Presence of a Histidine–Proline-Rich Peptide
The antiangiogenic activity of the H/P domain of histidine–proline-rich glycoprotein is mediated by its binding with tropomyosin, a protein exposed on endothelial cell-surface during the angiogenic switch, in presence of zinc ions. Although it is known that copper ion serum concentration is signific...
Autores principales: | Santoro, Anna Maria, Zimbone, Stefania, Magrì, Antonio, La Mendola, Diego, Grasso, Giulia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762548/ https://www.ncbi.nlm.nih.gov/pubmed/33302425 http://dx.doi.org/10.3390/ijms21249343 |
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