Cargando…

Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study

Toxicity induced by crizotinib, a small-molecule tyrosine kinase inhibitor, is a significant clinical issue during treatment. A tissue distribution study is required to explore the organs affected by this molecule. In this study, a simple liquid chromatography tandem mass spectrometry method was dev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Fang, Wei, Yuan, Yan, Yiming, Liu, Han, Zhou, Sitong, Ren, Bo, Liu, Ruijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762669/ https://www.ncbi.nlm.nih.gov/pubmed/33381185 http://dx.doi.org/10.1155/2020/8837254

Ejemplares similares

Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies
por: Feng, Qianru, et al.
Publicado: (2017)

Targeted Determination of Tissue Energy Status by LC-MS/MS
por: Fu, Xiaorong, et al.
Publicado: (2019)

Tissue pretreatment for LC–MS/MS analysis of PUFA and eicosanoid distribution in mouse brain and liver
por: Reinicke, Madlen, et al.
Publicado: (2019)

Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC–MS/MS and evaluation of their stability in mice tissues
por: Krijt, Jakub, et al.
Publicado: (2009)

Simultaneous Determination of RDX and HMX in Rat Plasma by LC-MS/MS and its Applications
por: Zhang, Xi, et al.
Publicado: (2022)

Pharmacokinetic analysis and tissue distribution of Vam3 in the rat by a validated LC-MS/MS method
por: Zhang, Ruixia, et al.
Publicado: (2015)

Plasmalogen Profiling in Porcine Brain Tissues by LC-MS/MS
por: Wu, Yue, et al.
Publicado: (2023)

Establishment of LC-MS/MS Method for Determination of GMDTC in Rat Plasma and Its Application in Preclinical Pharmacokinetics
por: Hu, Wei, et al.
Publicado: (2023)

Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats
por: Chen, Juan, et al.
Publicado: (2022)

A Selective and Sensitive LC-MS/MS Method for Quantitation of Indole in Mouse Serum and Tissues
por: Joshi, Vineet, et al.
Publicado: (2022)

Determination of dihydromyricetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study
por: Liu, Lu, et al.
Publicado: (2016)

LC–MS/MS Method for Simultaneous Determination of Linarin and Its Metabolites in Rat Plasma and Liver Tissue Samples: Application to Pharmacokinetic and Liver Tissue Distribution Study After Oral Administration of Linarin
por: Li, Yang, et al.
Publicado: (2019)

A highly sensitive LC-MS/MS method for quantitative determination of 7 vitamin D metabolites in mouse brain tissue
por: Stephenson, Andrea Joy, et al.
Publicado: (2023)

Development and validation of a sensitive LC-MS/MS method for pioglitazone: application towards pharmacokinetic and tissue distribution study in rats
por: G., Kusuma Kumari, et al.
Publicado: (2021)

Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
por: Liu, Yanping, et al.
Publicado: (2013)

Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS
por: Zeng, Qingyuan, et al.
Publicado: (2022)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
por: Gajula, Ramakrishna, et al.
Publicado: (2012)

Determination of cepharanthine in rat plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Deng, Yingbin, et al.
Publicado: (2017)

LC-ESI-LTQ-Orbitrap-MS for Profiling the Distribution of Oleacein and Its Metabolites in Rat Tissues
por: López-Yerena, Anallely, et al.
Publicado: (2021)

Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC–MS/MS
por: Hu, Wenjuan, et al.
Publicado: (2021)

Quantification of Acipimox in Plasma and Tissues by LC–MS/MS: Application to Pharmacokinetic Comparison between Normoxia and Hypoxia
por: Shen, Xin, et al.
Publicado: (2022)

Determination of Oxaliplatin by a UHPLC-MS/MS Method: Application to Pharmacokinetics and Tongue Tissue Distribution Studies in Rats
por: Gao, Xiuqing, et al.
Publicado: (2021)

Application of LC–MS/MS in the Mycotoxins Studies
por: Gámiz-Gracia, Laura, et al.
Publicado: (2020)

Validation by collaborative trial of a method for the determination by GC–MS and LC–MS/MS of boar taint marker compounds in pork tissue
por: Buttinger, Gerhard, et al.
Publicado: (2020)

LC-MS/MS Method for Determination of Hydroxychloroquine and Metabolites: Application in a Pharmacokinetic Study
por: Cui, Lili, et al.
Publicado: (2022)

Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
por: Zhang, Kai
Publicado: (2021)

Simultaneous Determination of Moxifloxacin Hydrochloride and Dexamethasone Sodium Phosphate in Rabbit Ocular Tissues and Plasma by LC-MS/MS: Application for Pharmacokinetics Studies
por: Zhao, Xinxin, et al.
Publicado: (2022)

Simultaneous determination of amlodipine, valsartan and hydrochlorothiazide by LC–ESI-MS/MS and its application to pharmacokinetics in rats
por: Gadepalli, Shankar Ganesh, et al.
Publicado: (2014)

Validated LC-MS/MS Method for the Determination of Scopoletin in Rat Plasma and Its Application to Pharmacokinetic Studies
por: Zeng, Yingchun, et al.
Publicado: (2015)

Absolute bioavailability, dose proportionality, and tissue distribution of rotundic acid in rats based on validated LC-QqQ-MS/MS method
por: Shang, Haihua, et al.
Publicado: (2022)

Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
por: Chaudhari, Kiran, et al.
Publicado: (2020)

Determination of Nine Fentanyl Drugs in Hair Samples by GC-MS/MS and LC-MS/MS
por: Wei, Qi, et al.
Publicado: (2022)

Determination of 355 Pesticides in Lemon and Lemon Juice by LC-MS/MS and GC-MS/MS
por: Aslantas, Sule, et al.
Publicado: (2023)

Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination
por: Zhang, Yue, et al.
Publicado: (2022)

Development and Application of Extraction Methods for LC-MS Quantification of Microcystins in Liver Tissue
por: Baliu-Rodriguez, David, et al.
Publicado: (2020)

Application of LC-MS/MS MRM to Determine Staphylococcal Enterotoxins (SEB and SEA) in Milk
por: Andjelkovic, Mirjana, et al.
Publicado: (2016)

Pharmacokinetics, tissue distribution, and metabolites of a polyvinylpyrrolidone-coated norcantharidin chitosan nanoparticle formulation in rats and mice, using LC-MS/MS
por: Ding, Xin-Yuan, et al.
Publicado: (2012)

Determination of asenapine in presence of its inactive metabolites in human plasma by LC-MS/MS
por: Patel, Nirav P., et al.
Publicado: (2018)

Determination of Salicylic Acid in Feed Using LC-MS/MS
por: Protasiuk, Edyta, et al.
Publicado: (2018)

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Lu, Wei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_j0l9vkgeco32542ru136q5puq5