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Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study

Toxicity induced by crizotinib, a small-molecule tyrosine kinase inhibitor, is a significant clinical issue during treatment. A tissue distribution study is required to explore the organs affected by this molecule. In this study, a simple liquid chromatography tandem mass spectrometry method was dev...

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Detalles Bibliográficos
Autores principales:	Zhao, Fang, Wei, Yuan, Yan, Yiming, Liu, Han, Zhou, Sitong, Ren, Bo, Liu, Ruijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762669/ https://www.ncbi.nlm.nih.gov/pubmed/33381185 http://dx.doi.org/10.1155/2020/8837254

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