Cargando…

Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro

Olaquindox (OLA), a member of the quinoxaline-N,N-dioxide family, has been widely used as a growth-promoting feed additive and treatment for bacterial infections. The toxicity has been a major concern, and the precise molecular mechanism remains poorly understood. The present study was aimed at inve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Daowen, Pei, Xingyao, Qin, Xiaoling, Liu, Xinyu, Li, Cun, Li, Liuan, Dai, Chongshan, Xiao, Xilong, Tang, Shusheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762677/ https://www.ncbi.nlm.nih.gov/pubmed/33381272 http://dx.doi.org/10.1155/2020/8835207

Ejemplares similares

GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways
por: Li, Daowen, et al.
Publicado: (2017)

TCS2 Increases Olaquindox-Induced Apoptosis by Upregulation of ROS Production and Downregulation of Autophagy in HEK293 Cells
por: Li, Daowen, et al.
Publicado: (2017)

Food-Origin Mycotoxin-Induced Neurotoxicity: Intend to Break the Rules of Neuroglia Cells
por: Pei, Xingyao, et al.
Publicado: (2021)

Curcumin Ameliorates Furazolidone-Induced DNA Damage and Apoptosis in Human Hepatocyte L02 Cells by Inhibiting ROS Production and Mitochondrial Pathway
por: Dai, Chongshan, et al.
Publicado: (2016)

Lethality of Zinc Oxide Nanoparticles Surpasses Conventional Zinc Oxide via Oxidative Stress, Mitochondrial Damage and Calcium Overload: A Comparative Hepatotoxicity Study
por: Pei, Xingyao, et al.
Publicado: (2022)

Identification of Plant Soot as Novel Safe Feed Additive: Evaluation of 90-Day Oral Toxicity and Prenatal Developmental Toxicity in Rats
por: Pei, Xingyao, et al.
Publicado: (2020)

Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis
por: Dai, Chongshan, et al.
Publicado: (2018)

Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways
por: Dai, Chongshan, et al.
Publicado: (2020)

Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells
por: Wu, Di, et al.
Publicado: (2017)

Development of Resistance in Escherichia coli ATCC25922 under Exposure of Sub-Inhibitory Concentration of Olaquindox
por: Gu, Yufeng, et al.
Publicado: (2020)

Evaluation of Embryotoxic Potential of Olaquindox and Vitamin A in Micromass Culture and in Rats
por: Kang, Hwan Goo, et al.
Publicado: (2010)

A Comprehensive Toxicological Assessment of Fulvic Acid
por: Dai, Chongshan, et al.
Publicado: (2020)

Pharmacokinetics and relative bioavailability of an oral amoxicillin-apramycin combination in pigs
por: Dai, Chongshan, et al.
Publicado: (2017)

Tissue Depletion of Olaquindox and Its Six Metabolites in Pigs and Broilers: Identification of a Suitable Marker Residue
por: Zhang, Heying, et al.
Publicado: (2021)

Engineered Geomedia Kaolin Clay-Reduced Graphene Oxide–Polymer Composite for the Remediation of Olaquindox from Water
por: Akpotu, Samson O., et al.
Publicado: (2022)

Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy
por: Zhang, Yuan, et al.
Publicado: (2022)

T-2 Toxin Induces Apoptotic Cell Death and Protective Autophagy in Mouse Microglia BV2 Cells
por: Sun, Tun, et al.
Publicado: (2022)

A Convenient and Sensitive LC-MS/MS Method for Simultaneous Determination of Carbadox- and Olaquindox-Related Residues in Swine Muscle and Liver Tissues
por: Zhang, Heying, et al.
Publicado: (2018)

Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway
por: Lin, Yanling, et al.
Publicado: (2022)

Novel Electrochemical Sensor Fabricated for Individual and Simultaneous Ultrasensitive Determination of Olaquindox and Carbadox Based on MWCNT-OH/CMK-8 Hybrid Nanocomposite Film
por: Liu, Yanqing, et al.
Publicado: (2019)

Inhibition of Oxidative Stress and ALOX12 and NF-κB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury
por: Dai, Chongshan, et al.
Publicado: (2021)

Surprising sirtuin crosstalk in the heart
por: Schug, Thaddeus T., et al.
Publicado: (2010)

Polymyxins–Curcumin Combination Antimicrobial Therapy: Safety Implications and Efficacy for Infection Treatment
por: Dai, Chongshan, et al.
Publicado: (2020)

Cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal cancer cells involves p53 and Hsp70
por: Wang, Fei, et al.
Publicado: (2023)

Off-line magnetic Fe(3)O(4)@SiO(2)@MIPs-based solid phase dispersion extraction coupling with HPLC for the simultaneous determination of olaquindox and its metabolite in fish muscle and milk samples
por: Tang, Yiwei, et al.
Publicado: (2023)

Crosstalk between p53 and TGF-β Signalling
por: Elston, Rebecca, et al.
Publicado: (2012)

TP53 and MTOR crosstalk to regulate cellular senescence
por: Galluzzi, Lorenzo, et al.
Publicado: (2010)

The inflammatory injury in the striatal microglia-dopaminergic-neuron crosstalk involved in Tourette syndrome development
por: Wang, Xueming, et al.
Publicado: (2023)

Nootkatone Supplementation Attenuates Carbon Tetrachloride Exposure-Induced Nephrotoxicity in Mice
por: Dai, Chongshan, et al.
Publicado: (2023)

Stepwise crosstalk between aberrant Nf1, Tp53 and Rb signalling pathways induces gliomagenesis in zebrafish
por: Luo, Juanjuan, et al.
Publicado: (2020)

Crosstalk between autophagy and CSCs: molecular mechanisms and translational implications
por: Li, Dai, et al.
Publicado: (2023)

The SLC25A1-p53 mutant crosstalk
por: Albanese, Chris, et al.
Publicado: (2015)

Biosynthesis of Fungal Natural Products Involving Two Separate Pathway Crosstalk
por: Dai, Guangzhi, et al.
Publicado: (2022)

Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys
por: Peng, Hui, et al.
Publicado: (2017)

Uncovering miRNAs involved in crosstalk between nutrient deficiencies in Arabidopsis
por: Liang, Gang, et al.
Publicado: (2015)

Aflatoxin B1 Toxicity and Protective Effects of Curcumin: Molecular Mechanisms and Clinical Implications
por: Dai, Chongshan, et al.
Publicado: (2022)

Tumor Suppressor P53 Binding Protein 1 (53bp1) Is Involved in DNA Damage–Signaling Pathways
por: Rappold, Irene, et al.
Publicado: (2001)

Micronuclei to detect in vivo chemotherapy damage in a p53 mutated solid tumour
por: Driessens, G, et al.
Publicado: (2003)

Selenium-chitosan alleviates the toxic effects of Zearalenone on antioxidant and immune function in mice
por: Qin, Shunyi, et al.
Publicado: (2022)

Mutant p53—a potential player in shaping the tumor–stroma crosstalk
por: Stein, Yan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_a5au51hm35p68tq58n95qtjmtq