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Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons
Hydroxychloroquine is being investigated for a potential prophylactic effect in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but its mechanism of action is poorly understood. Circulating leukocytes from the blood of coronavirus disease 2019 (COVID-19) patients show increas...
Autores principales: | Rother, Nils, Yanginlar, Cansu, Lindeboom, Rik G.H., Bekkering, Siroon, van Leent, Mandy M.T., Buijsers, Baranca, Jonkman, Inge, de Graaf, Mark, Baltissen, Marijke, Lamers, Lieke A., Riksen, Niels P., Fayad, Zahi A., Mulder, Willem J.M., Hilbrands, Luuk B., Joosten, Leo A.B., Netea, Mihai G., Vermeulen, Michiel, van der Vlag, Johan, Duivenvoorden, Raphaël |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762774/ https://www.ncbi.nlm.nih.gov/pubmed/33377122 http://dx.doi.org/10.1016/j.xcrm.2020.100146 |
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