Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription

Thoracic great vessels such as the aorta and subclavian arteries are formed through dynamic remodeling of embryonic pharyngeal arch arteries (PAAs). Previous work has shown that loss of a basic helix-loop-helix transcription factor Hey1 in mice causes abnormal fourth PAA development and lethal great...

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Detalles Bibliográficos
Autores principales: Watanabe, Yusuke, Seya, Daiki, Ihara, Dai, Ishii, Shuhei, Uemoto, Taiki, Kubo, Atsushi, Arai, Yuji, Isomoto, Yoshie, Nakano, Atsushi, Abe, Takaya, Shigeta, Mayo, Kawamura, Teruhisa, Saito, Yoshihiko, Ogura, Toshihiko, Nakagawa, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762959/
https://www.ncbi.nlm.nih.gov/pubmed/33454003
http://dx.doi.org/10.1074/jbc.RA120.015003

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