Cargando…

Approaching Shared Pathophysiology in Immune-Mediated Diseases through Functional Genomics

Immune-mediated diseases (IMDs) are complex pathologies that are strongly influenced by environmental and genetic factors. Associations between genetic loci and susceptibility to these diseases have been widely studied, and hundreds of risk variants have emerged during the last two decades, with res...

Descripción completa

Detalles Bibliográficos
Autores principales:	González-Serna, David, Villanueva-Martin, Gonzalo, Acosta-Herrera, Marialbert, Márquez, Ana, Martín, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762979/ https://www.ncbi.nlm.nih.gov/pubmed/33317201 http://dx.doi.org/10.3390/genes11121482

Ejemplares similares

The Potential Role of Genomic Medicine in the Therapeutic Management of Rheumatoid Arthritis
por: Acosta-Herrera, Marialbert, et al.
Publicado: (2019)

Leveraging Genetic Findings for Precision Medicine in Vasculitis
por: Acosta-Herrera, Marialbert, et al.
Publicado: (2019)

FLT3 functional low-frequency variant rs76428106-C is associated with susceptibility to systemic sclerosis
por: Martínez-López, Javier, et al.
Publicado: (2022)

Contribution of Telomere Length to Systemic Sclerosis Onset: A Mendelian Randomization Study
por: Rodriguez-Martin, Inmaculada, et al.
Publicado: (2023)

GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels
por: Casares-Marfil, Desiré, et al.
Publicado: (2021)

Comprehensive analysis of three TYK2 gene variants in the susceptibility to Chagas disease infection and cardiomyopathy
por: Leon Rodriguez, Daniel A., et al.
Publicado: (2018)

Association of IL18 genetic polymorphisms with Chagas disease in Latin American populations
por: Strauss, Mariana, et al.
Publicado: (2019)

Immune-Mediated Neuropathies: Pathophysiology and Management
por: Shastri, Abhishek, et al.
Publicado: (2023)

Genetic polymorphisms of IL17A associated with Chagas disease: results from a meta-analysis in Latin American populations
por: Strauss, Mariana, et al.
Publicado: (2020)

Narcolepsy and Psychiatric Disorders: Comorbidities or Shared Pathophysiology?
por: Morse, Anne Marie, et al.
Publicado: (2018)

Assessing the quality of studies supporting genetic susceptibility and outcomes of ARDS
por: Acosta-Herrera, Marialbert, et al.
Publicado: (2014)

Psoriasis as an Immune-Mediated and Inflammatory Systemic Disease: From Pathophysiology to Novel Therapeutic Approaches
por: Campanati, Anna, et al.
Publicado: (2021)

A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn’s disease
por: González-Serna, David, et al.
Publicado: (2020)

Epithelial Transport in Disease: An Overview of Pathophysiology and Treatment
por: Clemente-Suárez, Vicente Javier, et al.
Publicado: (2023)

Shared and independent roles of CGRP and PACAP in migraine pathophysiology
por: Kuburas, Adisa, et al.
Publicado: (2023)

Lactic Acid Transport Mediated by Aquaporin-9: Implications on the Pathophysiology of Preeclampsia
por: Medina, Yollyseth, et al.
Publicado: (2021)

Pathophysiology of Immune Checkpoint Inhibitor-Induced Myocarditis
por: Jiménez-Alejandre, Rosa, et al.
Publicado: (2022)

Association of Tinnitus and Electromagnetic Hypersensitivity: Hints for a Shared Pathophysiology?
por: Landgrebe, Michael, et al.
Publicado: (2009)

Image-Based Airborne Sensors: A Combined Approach for Spectral Signatures Classification through Deterministic Simulated Annealing
por: Guijarro, María, et al.
Publicado: (2009)

-Omic Approaches and Treatment Response in Rheumatoid Arthritis
por: Madrid-Paredes, Adela, et al.
Publicado: (2022)

Hippocampal Pathophysiology: Commonality Shared by Temporal Lobe Epilepsy and Psychiatric Disorders
por: Nakahara, Soichiro, et al.
Publicado: (2018)

Metabolic Syndrome and Overactive Bladder Syndrome May Share Common Pathophysiologies
por: Hsu, Lin-Nei, et al.
Publicado: (2022)

Admixture mapping analysis reveals differential genetic ancestry associated with Chagas disease susceptibility in the Colombian population
por: Casares-Marfil, Desiré, et al.
Publicado: (2021)

Pathophysiology of Atherosclerosis
por: Jebari-Benslaiman, Shifa, et al.
Publicado: (2022)

Leptospirosis Pathophysiology: Into the Storm of Cytokines
por: Cagliero, Julie, et al.
Publicado: (2018)

The Effect of Body Fat Distribution on Systemic Sclerosis
por: Villanueva-Martin, Gonzalo, et al.
Publicado: (2022)

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
por: Pouget, Jennie G, et al.
Publicado: (2019)

The Role of ABA in Plant Immunity is Mediated through the PYR1 Receptor
por: García-Andrade, Javier, et al.
Publicado: (2020)

Pathophysiology and Immune Dysfunction in Endometriosis
por: Ahn, Soo Hyun, et al.
Publicado: (2015)

Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity
por: Oka, Takehiko, et al.
Publicado: (2010)

Exploration of the shared pathophysiological mechanisms of gestational diabetes and large for gestational age offspring
por: Nahavandi, Sofia, et al.
Publicado: (2019)

Diabetes Mellitus and Parkinson's Disease: Shared Pathophysiological Links and Possible Therapeutic Implications
por: Hassan, Abdallah, et al.
Publicado: (2020)

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System
por: Saez, Angela, et al.
Publicado: (2023)

Genomics of Otitis Media (OM): Molecular Genetics Approaches to Characterize Disease Pathophysiology
por: Giese, Arnaud P. J., et al.
Publicado: (2020)

Lymphocyte DNA methylation mediates genetic risk at shared immune-mediated disease loci
por: Clark, Alexander D., et al.
Publicado: (2020)

Schnitzler’s syndrome - a novel hypothesis of a shared pathophysiologic mechanism with Waldenström’s disease
por: van Leersum, FS, et al.
Publicado: (2019)

Renal Contributions in the Pathophysiology and Neuropathological Substrates Shared by Chronic Kidney Disease and Alzheimer’s Disease
por: Stanciu, Gabriela Dumitrita, et al.
Publicado: (2020)

MAFLD vs. NAFLD: shared features and potential changes in epidemiology, pathophysiology, diagnosis, and pharmacotherapy
por: Xian, Ying-Xin, et al.
Publicado: (2021)

Mechanisms, Pathophysiology and Current Immunomodulatory/Immunosuppressive Therapy of Non-Infectious and/or Immune-Mediated Choroiditis
por: Papasavvas, Ioannis, et al.
Publicado: (2022)

Pathophysiological Mechanisms and Treatment of Dermatomyositis and Immune Mediated Necrotizing Myopathies: A Focused Review
por: Kamperman, Renske G., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4gdatl5ag8jgukr2vfbtsqmt48