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U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing

Splicing factor 3b subunit 1 (SF3B1) is an essential protein in spliceosomes and mutated frequently in many cancers. While roles of SF3B1 in single intron splicing and roles of its cancer-linked mutant in aberrant splicing have been identified to some extent, regulatory functions of wild-type SF3B1...

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Detalles Bibliográficos
Autores principales: Choi, Namjeong, Liu, Yongchao, Oh, Jagyeong, Ha, Jiyeon, Zheng, Xuexiu, Shen, Haihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762998/
https://www.ncbi.nlm.nih.gov/pubmed/33317029
http://dx.doi.org/10.3390/cells9122647