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Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels
Preemptive management of post-incisional pain remains challenging. Here, we examined the role of preemptive use of neuroactive steroids with activity on low-voltage activated T-type Ca(2+) channels (T-channels) and γ-aminobutyric acid A (GABA(A)) receptors in the development and maintenance of post-...
Autores principales: | Tat, Quy L., Joksimovic, Srdjan M., Krishnan, Kathiresan, Covey, Douglas F., Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763050/ https://www.ncbi.nlm.nih.gov/pubmed/33322727 http://dx.doi.org/10.3390/cells9122674 |
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