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Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels

Preemptive management of post-incisional pain remains challenging. Here, we examined the role of preemptive use of neuroactive steroids with activity on low-voltage activated T-type Ca(2+) channels (T-channels) and γ-aminobutyric acid A (GABA(A)) receptors in the development and maintenance of post-...

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Detalles Bibliográficos
Autores principales: Tat, Quy L., Joksimovic, Srdjan M., Krishnan, Kathiresan, Covey, Douglas F., Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763050/
https://www.ncbi.nlm.nih.gov/pubmed/33322727
http://dx.doi.org/10.3390/cells9122674

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