Cargando…
Fibrosis Distinguishes Critical Limb Ischemia Patients from Claudicants in a Transcriptomic and Histologic Analysis
Most patients with critical limb ischemia (CLI) from peripheral arterial disease (PAD) do not have antecedent intermittent claudication (IC). We hypothesized that transcriptomic analysis would identify CLI-specific pathways, particularly in regards to fibrosis. Derivation cohort data from muscle bio...
Autores principales: | Cong, Guangzhi, Cui, Xiangdong, Ferrari, Ricardo, Pipinos, Iraklis I., Casale, George P., Chattopadhyay, Ansuman, Sachdev, Ulka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763090/ https://www.ncbi.nlm.nih.gov/pubmed/33302519 http://dx.doi.org/10.3390/jcm9123974 |
Ejemplares similares
-
Abnormal Microvascular Architecture, Fibrosis, and Pericyte Characteristics in the Calf Muscle of Peripheral Artery Disease Patients with Claudication and Critical Limb Ischemia
por: Mietus, Constance J., et al.
Publicado: (2020) -
TLR2 and TLR4 Mediate Differential Responses to Limb Ischemia through MyD88-Dependent and Independent Pathways
por: Sachdev, Ulka, et al.
Publicado: (2012) -
Compared to Intermittant Claudication Critical Limb Ischemia Is Associated with Elevated Levels of Cytokines
por: Jalkanen, Juho, et al.
Publicado: (2016) -
Low serum vitamin C correlates with an increased risk of peripheral arterial disease in current smokers: Results from NHANES 2003–2004
por: Cong, Guangzhi, et al.
Publicado: (2020) -
Peripheral artery disease affects the function of the legs of claudicating patients in a diffuse manner irrespective of the segment of the arterial tree primarily involved
por: Leutzinger, Todd J., et al.
Publicado: (2022)