Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist

Preclinical studies highlighted that compounds targeting cannabinoid receptors could be useful for developing novel therapies against neurodegenerative disorders. However, the chronic use of orthosteric agonists alone has several disadvantages, limiting their usefulness as clinically relevant drugs....

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Detalles Bibliográficos
Autores principales: Polini, Beatrice, Cervetto, Chiara, Carpi, Sara, Pelassa, Simone, Gado, Francesca, Ferrisi, Rebecca, Bertini, Simone, Nieri, Paola, Marcoli, Manuela, Manera, Clementina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763181/
https://www.ncbi.nlm.nih.gov/pubmed/33302569
http://dx.doi.org/10.3390/life10120333

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