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Hereditary Diffuse Gastric Cancer: A Comparative Cohort Study According to Pathogenic Variant Status

SIMPLE SUMMARY: Pathogenic germline variants in CDH1 and CTNNA1 lead to a high prevalence of diffuse gastric cancer and breast cancer in carrier families. However, in most families with hereditary diffuse gastric cancer syndrome, the underlying genetic alteration remains elusive. In this cohort stud...

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Detalles Bibliográficos
Autores principales: Marwitz, Tim, Hüneburg, Robert, Spier, Isabel, Lau, Jan-Frederic, Kristiansen, Glen, Lingohr, Philipp, Kalff, Jörg C., Aretz, Stefan, Nattermann, Jacob, Strassburg, Christian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763201/
https://www.ncbi.nlm.nih.gov/pubmed/33322525
http://dx.doi.org/10.3390/cancers12123726