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Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms
Manganese (Mn) is an essential trace element, serving as a cofactor for several key enzymes, such as glutamine synthetase, arginase, pyruvate decarboxylase, and mitochondrial superoxide dismutase. However, its chronic overexposure can result in a neurological disorder referred to as manganism, prese...
Autores principales: | Nyarko-Danquah, Ivan, Pajarillo, Edward, Digman, Alexis, Soliman, Karam F. A., Aschner, Michael, Lee, Eunsook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763224/ https://www.ncbi.nlm.nih.gov/pubmed/33322668 http://dx.doi.org/10.3390/molecules25245880 |
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