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Pharmacological Inhibition of O-GlcNAc Transferase Promotes mTOR-Dependent Autophagy in Rat Cortical Neurons

O-GlcNAc transferase (OGT) is a ubiquitous enzyme that regulates the addition of β-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues of target proteins. Autophagy is a cellular process of self-digestion, in which cytoplasmic resources, such as aggregate proteins, toxic compounds, damag...

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Detalles Bibliográficos
Autores principales:	Rahman, Md. Ataur, Cho, Yoonjeong, Hwang, Hongik, Rhim, Hyewhon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763293/ https://www.ncbi.nlm.nih.gov/pubmed/33317171 http://dx.doi.org/10.3390/brainsci10120958

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