Cargando…

Thioredoxin and Glutaredoxin Systems as Potential Targets for the Development of New Treatments in Friedreich’s Ataxia

The thioredoxin family consists of a small group of redox proteins present in all organisms and composed of thioredoxins (TRXs), glutaredoxins (GLRXs) and peroxiredoxins (PRDXs) which are found in the extracellular fluid, the cytoplasm, the mitochondria and in the nucleus with functions that include...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seco-Cervera, Marta, González-Cabo, Pilar, Pallardó, Federico V., Romá-Mateo, Carlos, García-Giménez, José Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763308/ https://www.ncbi.nlm.nih.gov/pubmed/33321938 http://dx.doi.org/10.3390/antiox9121257

Ejemplares similares

Small RNA-seq analysis of circulating miRNAs to identify phenotypic variability in Friedreich’s ataxia patients
por: Seco-Cervera, Marta, et al.
Publicado: (2018)

Circulating miR-323-3p is a biomarker for cardiomyopathy and an indicator of phenotypic variability in Friedreich’s ataxia patients
por: Seco-Cervera, M., et al.
Publicado: (2017)

Differential Expression of PGC-1α and Metabolic Sensors Suggest Age-Dependent Induction of Mitochondrial Biogenesis in Friedreich Ataxia Fibroblasts
por: García-Giménez, José Luis, et al.
Publicado: (2011)

Oxidative stress modulates rearrangement of endoplasmic reticulum-mitochondria contacts and calcium dysregulation in a Friedreich's ataxia model
por: Rodríguez, Laura R., et al.
Publicado: (2020)

Friedreich's Ataxia
por: Anderson, J. Wallace
Publicado: (1893)

Thioredoxin and Glutaredoxin Systems Antioxidants Special Issue
por: Jacquot, Jean-Pierre, et al.
Publicado: (2019)

Much More Than a Scaffold: Cytoskeletal Proteins in Neurological Disorders
por: Muñoz-Lasso, Diana C., et al.
Publicado: (2020)

The Role of Iron in Friedreich’s Ataxia: Insights From Studies in Human Tissues and Cellular and Animal Models
por: Llorens, José Vicente, et al.
Publicado: (2019)

The specificity of thioredoxins and glutaredoxins is determined by electrostatic and geometric complementarity
por: Berndt, Carsten, et al.
Publicado: (2015)

The Pathology of Friedreich's Ataxia
por: Rainy, Harry
Publicado: (1905)

Neuroinflammation in Friedreich’s Ataxia
por: Apolloni, Savina, et al.
Publicado: (2022)

Antioxidant Therapies and Oxidative Stress in Friedreich’s Ataxia: The Right Path or Just a Diversion?
por: Rodríguez, Laura R., et al.
Publicado: (2020)

Neuro-Ophthalmological Findings in Friedreich’s Ataxia
por: Rojas, Pilar, et al.
Publicado: (2021)

Frataxin Deficit Leads to Reduced Dynamics of Growth Cones in Dorsal Root Ganglia Neurons of Friedreich’s Ataxia YG8sR Model: A Multilinear Algebra Approach
por: Muñoz-Lasso, Diana C., et al.
Publicado: (2022)

Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches
por: López-Grueso, MJ, et al.
Publicado: (2018)

Substrate specificity of thioredoxins and glutaredoxins – towards a functional classification
por: Gellert, Manuela, et al.
Publicado: (2019)

Redox regulation, thioredoxins, and glutaredoxins in retrograde signalling and gene transcription
por: Sevilla, Francisca, et al.
Publicado: (2023)

Drosophila melanogaster Models of Friedreich's Ataxia
por: Calap-Quintana, P., et al.
Publicado: (2018)

Is Friedreich ataxia an epigenetic disorder?
por: Kumari, Daman, et al.
Publicado: (2012)

The Pathogenesis of Cardiomyopathy in Friedreich Ataxia
por: Koeppen, Arnulf H., et al.
Publicado: (2015)

Depressive symptoms in Friedreich ataxia
por: Nieto, Antonieta, et al.
Publicado: (2018)

Heart disease in Friedreich’s ataxia
por: Hanson, Emily, et al.
Publicado: (2019)

Drug Repositioning in Friedreich Ataxia
por: Rufini, Alessandra, et al.
Publicado: (2022)

Two Cases of Friedreich’s Ataxia
por: Stephenson, F. H.
Publicado: (1897)

Respiratory Function in Friedreich’s Ataxia
por: Vinante, Elena, et al.
Publicado: (2022)

Thioredoxin/Glutaredoxin Systems and Gut Microbiota in NAFLD: Interplay, Mechanism, and Therapeutical Potential
por: Zhu, Minghui, et al.
Publicado: (2023)

Deferiprone targets aconitase: Implication for Friedreich's ataxia treatment
por: Goncalves, Sergio, et al.
Publicado: (2008)

Central Nervous System Therapeutic Targets in Friedreich Ataxia
por: Harding, Ian H., et al.
Publicado: (2020)

Oxidative Stress and Epigenetics: miRNA Involvement in Rare Autoimmune Diseases
por: Ibáñez-Cabellos, José Santiago, et al.
Publicado: (2023)

Structural Analysis of Glutaredoxin Domain of Mus musculus Thioredoxin Glutathione Reductase
por: Dobrovolska, Olena, et al.
Publicado: (2012)

Friedreich ataxia in a family from Mali, West Africa/Friedreich ataxia in a Malian family
por: Cissé, Cheick A. K., et al.
Publicado: (2021)

Anaesthesia for a patient with Friedreich's ataxia
por: Ganesan, Ilango
Publicado: (2011)

Hepatic mitochondrial dysfunction in Friedreich Ataxia
por: Stüwe, Sven H, et al.
Publicado: (2011)

Epigenetic-based therapies for Friedreich ataxia
por: Sandi, Chiranjeevi, et al.
Publicado: (2014)

Identification of telomere dysfunction in Friedreich ataxia
por: Anjomani Virmouni, Sara, et al.
Publicado: (2015)

Otoneurological Abnormalities in Patients with Friedreich's Ataxia
por: Zeigelboim, Bianca Simone, et al.
Publicado: (2016)

The role of oxidative stress in Friedreich's ataxia
por: Lupoli, Federica, et al.
Publicado: (2017)

Two Cases of Friedreich's Ataxia in Adolescents
por: Fergus, John
Publicado: (1917)

Autonomic function testing in Friedreich’s ataxia
por: Indelicato, Elisabetta, et al.
Publicado: (2018)

An Overview of the Ferroptosis Hallmarks in Friedreich’s Ataxia
por: Turchi, Riccardo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k5ii4cginmpaph7blt15h2idd4