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Hydroxylumisterols, Photoproducts of Pre-Vitamin D3, Protect Human Keratinocytes against UVB-Induced Damage
Lumisterol (L3) is a stereoisomer of 7-dehydrocholesterol and is produced through the photochemical transformation of 7-dehydrocholesteol induced by high doses of UVB. L3 is enzymatically hydroxylated by CYP11A1, producing 20(OH)L3, 22(OH)L3, 20,22(OH)2L3, and 24(OH)L3. Hydroxylumisterols function a...
Autores principales: | Chaiprasongsuk, Anyamanee, Janjetovic, Zorica, Kim, Tae-Kang, Schwartz, Cynthia J., Tuckey, Robert C., Tang, Edith K. Y., Raman, Chander, Panich, Uraiwan, Slominski, Andrzej T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763359/ https://www.ncbi.nlm.nih.gov/pubmed/33317048 http://dx.doi.org/10.3390/ijms21249374 |
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