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Identification of Key Small Non‐Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node

BACKGROUND: The sinus node (SN) is the primary pacemaker of the heart. SN myocytes possess distinctive action potential morphology with spontaneous diastolic depolarization because of a unique expression of ion channels and Ca(2+)‐handling proteins. MicroRNAs (miRs) inhibit gene expression. The role...

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Detalles Bibliográficos
Autores principales: Petkova, Maria, Atkinson, Andrew J., Yanni, Joseph, Stuart, Luke, Aminu, Abimbola J., Ivanova, Alexandra D., Pustovit, Ksenia B., Geragthy, Connor, Feather, Amy, Li, Ning, Zhang, Yu, Oceandy, Delvac, Perde, Filip, Molenaar, Peter, D’Souza, Alicia, Fedorov, Vadim V., Dobrzynski, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763385/
https://www.ncbi.nlm.nih.gov/pubmed/33059532
http://dx.doi.org/10.1161/JAHA.120.016590

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