Cargando…
Identification of Key Small Non‐Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node
BACKGROUND: The sinus node (SN) is the primary pacemaker of the heart. SN myocytes possess distinctive action potential morphology with spontaneous diastolic depolarization because of a unique expression of ion channels and Ca(2+)‐handling proteins. MicroRNAs (miRs) inhibit gene expression. The role...
Autores principales: | Petkova, Maria, Atkinson, Andrew J., Yanni, Joseph, Stuart, Luke, Aminu, Abimbola J., Ivanova, Alexandra D., Pustovit, Ksenia B., Geragthy, Connor, Feather, Amy, Li, Ning, Zhang, Yu, Oceandy, Delvac, Perde, Filip, Molenaar, Peter, D’Souza, Alicia, Fedorov, Vadim V., Dobrzynski, Halina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763385/ https://www.ncbi.nlm.nih.gov/pubmed/33059532 http://dx.doi.org/10.1161/JAHA.120.016590 |
Ejemplares similares
-
Sinus node-like pacemaker mechanisms regulate ectopic pacemaker activity in the adult rat atrioventricular ring
por: Logantha, Sunil Jit R. J., et al.
Publicado: (2019) -
TBX18 overexpression enhances pacemaker function in a rat subsidiary atrial pacemaker model of sick sinus syndrome
por: Choudhury, M., et al.
Publicado: (2018) -
Silencing miR-370-3p rescues funny current and sinus node function in heart failure
por: Yanni, Joseph, et al.
Publicado: (2020) -
Structural and Functional Properties of Subsidiary Atrial Pacemakers in a Goat Model of Sinus Node Disease
por: Soattin, Luca, et al.
Publicado: (2021) -
RNAseq shows an all-pervasive day-night rhythm in the transcriptome of the pacemaker of the heart
por: Wang, Yanwen, et al.
Publicado: (2021)