Cargando…

Modulating the Crosstalk between the Tumor and the Microenvironment Using SiRNA: A Flexible Strategy for Breast Cancer Treatment

SIMPLE SUMMARY: With this review we aimed to collect the most relevant scientific findings regarding siRNA therapeutic tools against breast cancer microenvironment. Remarkably, breast cancer treatments have been redirected towards the tumor microenvironment components, mainly involved in patients’ r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roscigno, Giuseppina, Scognamiglio, Iolanda, Ingenito, Francesco, Chianese, Rosario Vincenzo, Palma, Francesco, Chan, Alan, Condorelli, Gerolama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763441/ https://www.ncbi.nlm.nih.gov/pubmed/33322132 http://dx.doi.org/10.3390/cancers12123744

Ejemplares similares

The Role of Exo-miRNAs in Cancer: A Focus on Therapeutic and Diagnostic Applications
por: Ingenito, Francesco, et al.
Publicado: (2019)

miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment
por: Roscigno, Giuseppina, et al.
Publicado: (2020)

Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer
por: Scognamiglio, Iolanda, et al.
Publicado: (2022)

Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer
por: Scognamiglio, Iolanda, et al.
Publicado: (2022)

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer
por: Palma, Francesco, et al.
Publicado: (2020)

Potential and Challenges of Aptamers as Specific Carriers of Therapeutic Oligonucleotides for Precision Medicine in Cancer
por: Nuzzo, Silvia, et al.
Publicado: (2019)

Comparative Proteomic Profiling of Secreted Extracellular Vesicles from Breast Fibroadenoma and Malignant Lesions: A Pilot Study
por: Pane, Katia, et al.
Publicado: (2022)

Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
por: Esposito, Carla Lucia, et al.
Publicado: (2021)

Targeting Ephrin Receptor Tyrosine Kinase A2 with a Selective Aptamer for Glioblastoma Stem Cells
por: Affinito, Alessandra, et al.
Publicado: (2020)

Aptamer-miR-34c Conjugate Affects Cell Proliferation of Non-Small-Cell Lung Cancer Cells
por: Russo, Valentina, et al.
Publicado: (2018)

RYK promotes the stemness of glioblastoma cells via the WNT/β-catenin pathway
por: Adamo, Assunta, et al.
Publicado: (2017)

MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer
por: Roscigno, Giuseppina, et al.
Publicado: (2017)

Pulmonary delivery of therapeutic siRNA
por: Lam, Jenny Ka-Wing, et al.
Publicado: (2012)

Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes
por: Liang, XueJiao, et al.
Publicado: (2020)

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL
por: Iaboni, Margherita, et al.
Publicado: (2016)

Enzyme-triggered PEGylated siRNA-nanoparticles for controlled release of siRNA
por: Yingyuad, Peerada, et al.
Publicado: (2014)

Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
por: Berezhnoy, Alexey, et al.
Publicado: (2012)

Where should siRNAs go: applicable organs for siRNA drugs
por: Ahn, Insook, et al.
Publicado: (2023)

Remodeling the tumor immune microenvironment via siRNA therapy for precision cancer treatment
por: Jiang, Lingxi, et al.
Publicado: (2023)

Therapeutic siRNA: Principles, Challenges, and Strategies
por: Gavrilov, Kseniya, et al.
Publicado: (2012)

Engineering siRNA therapeutics: challenges and strategies
por: Ali Zaidi, Syed Saqib, et al.
Publicado: (2023)

miR-221/222 Target the DNA Methyltransferase MGMT in Glioma Cells
por: Quintavalle, Cristina, et al.
Publicado: (2013)

Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro
por: Yang, Wenqian, et al.
Publicado: (2021)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

siRNA for Influenza Therapy
por: Barik, Sailen
Publicado: (2010)

Retrovirus-delivered siRNA
por: Devroe, Eric, et al.
Publicado: (2002)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Genome-wide screens for effective siRNAs through assessing the size of siRNA effects
por: Zhang, Xiaohua Douglas
Publicado: (2008)

Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities
por: Ichihara, Masatoshi, et al.
Publicado: (2007)

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
por: Ballarín-González, Borja, et al.
Publicado: (2013)

Strategies for Delivery of siRNAs to Ovarian Cancer Cells
por: Farra, Rossella, et al.
Publicado: (2019)

An Overview of siRNA Delivery Strategies for Urological Cancers
por: Halib, Nadia, et al.
Publicado: (2022)

sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
por: Shah, Jyoti K, et al.
Publicado: (2007)

Expression data of HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the presence of BubR1 siRNA
por: Nakayama, Yusuke, et al.
Publicado: (2015)

Lipid and Polymer-Based Nanoparticle siRNA Delivery Systems for Cancer Therapy
por: Mainini, Francesco, et al.
Publicado: (2020)

Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer
por: Donnarumma, Elvira, et al.
Publicado: (2017)

siRNAdb: a database of siRNA sequences
por: Chalk, Alistair M., et al.
Publicado: (2005)

siRNAdb: a database of siRNA sequences
por: Chalk, Alistair M., et al.
Publicado: (2005)

Effect of Erdosteine on Cyclosporine Induced Chronic Nephrotoxicity
por: Briguori, Carlo, et al.
Publicado: (2012)

Design of siRNA Therapeutics from the Molecular Scale
por: Angart, Phillip, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_d1mq20s2s2poknlmq8dthtjk3d