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Quantifying the Monomer–Dimer Equilibrium of Tubulin with Mass Photometry

The [Formula: see text]-tubulin heterodimer is the fundamental building block of microtubules, making it central to several cellular processes. Despite the apparent simplicity of heterodimerisation, the associated energetics and kinetics remain disputed, largely due to experimental challenges associ...

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Detalles Bibliográficos
Autores principales: Fineberg, Adam, Surrey, Thomas, Kukura, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763485/
https://www.ncbi.nlm.nih.gov/pubmed/33068635
http://dx.doi.org/10.1016/j.jmb.2020.10.013