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TET1 Interacts Directly with NANOG via Independent Domains Containing Hydrophobic and Aromatic Residues

The DNA demethylase TET1 is highly expressed in embryonic stem cells and is important both for lineage commitment, and reprogramming to naïve pluripotency. TET1 interacts with the pluripotency transcription factor NANOG which may contribute to its biological activity in pluripotent cells. However, h...

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Detalles Bibliográficos
Autores principales: Pantier, Raphaël, Mullin, Nicholas, Hall-Ponsele, Elisa, Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763487/
https://www.ncbi.nlm.nih.gov/pubmed/33058869
http://dx.doi.org/10.1016/j.jmb.2020.10.008

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