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TET1 Interacts Directly with NANOG via Independent Domains Containing Hydrophobic and Aromatic Residues
The DNA demethylase TET1 is highly expressed in embryonic stem cells and is important both for lineage commitment, and reprogramming to naïve pluripotency. TET1 interacts with the pluripotency transcription factor NANOG which may contribute to its biological activity in pluripotent cells. However, h...
Autores principales: | Pantier, Raphaël, Mullin, Nicholas, Hall-Ponsele, Elisa, Chambers, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763487/ https://www.ncbi.nlm.nih.gov/pubmed/33058869 http://dx.doi.org/10.1016/j.jmb.2020.10.008 |
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