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Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection

A prophylactic HIV vaccine would ideally induce protective immunity prior to sexual debut. Children develop broadly neutralizing antibody (bnAb) responses faster and at higher frequencies than adults, but little is known about the underlying mechanisms or the potential role of Fc-mediated effector f...

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Detalles Bibliográficos
Autores principales: Muenchhoff, M., Chung, A. W., Roider, J., Dugast, Anne-Sophie, Richardson, Simone, Kløverpris, Henrik, Leslie, Alasdair, Ndung’u, Thumbi, Moore, Penny, Alter, Galit, Goulder, Philip J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763548/
https://www.ncbi.nlm.nih.gov/pubmed/33361123
http://dx.doi.org/10.1128/mSphere.00880-20

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