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The Two-Component System CopRS Maintains Subfemtomolar Levels of Free Copper in the Periplasm of Pseudomonas aeruginosa Using a Phosphatase-Based Mechanism

Two-component systems control periplasmic Cu(+) homeostasis in Gram-negative bacteria. In characterized systems such as Escherichia coli CusRS, upon Cu(+) binding to the periplasmic sensing region of CusS, a cytoplasmic phosphotransfer domain of the sensor phosphorylates the response regulator CusR....

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Detalles Bibliográficos
Autores principales:	Novoa-Aponte, Lorena, Xu, Cheng, Soncini, Fernando C., Argüello, José M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763554/ https://www.ncbi.nlm.nih.gov/pubmed/33361129 http://dx.doi.org/10.1128/mSphere.01193-20

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