Cargando…
Assessing Prognostic and Predictive Biomarkers of Regorafenib Response in Patients with Advanced Soft Tissue Sarcoma: REGOSARC Study
SIMPLE SUMMARY: In a double-blind, placebo-controlled, randomized phase 2 trial, Regorafenib provided a clinical benefit to patients with advanced and anthracycline-pretreated soft tissue sarcoma. However, extensive mutational analysis of tumor genes could not identify predictive markers of regorafe...
Autores principales: | Brodowicz, Thomas, Liegl-Atzwanger, Bernadette, Penel, Nicolas, Mir, Olivier, Blay, Jean-Yves, Kashofer, Karl, Le Cesne, Axel, Decoupigny, Emilie, Wallet, Jennifer, Hamacher, Rainer, Le Deley, Marie-Cecile |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763753/ https://www.ncbi.nlm.nih.gov/pubmed/33322802 http://dx.doi.org/10.3390/cancers12123746 |
Ejemplares similares
-
REGOSARC: Regorafenib versus placebo in doxorubicin‐refractory soft‐tissue sarcoma—A quality‐adjusted time without symptoms of progression or toxicity analysis
por: Berry, Vincent, et al.
Publicado: (2017) -
Study protocol of REGOSARC trial: activity and safety of regorafenib in advanced soft tissue sarcoma: a multinational, randomized, placebo-controlled, phase II trial
por: Brodowicz, Thomas, et al.
Publicado: (2015) -
Diagnosis and treatment of soft-tissue sarcomas of the extremities and trunk
por: Smolle, Maria Anna, et al.
Publicado: (2017) -
Detection of GNAS mutations in intramuscular / cellular myxomas as diagnostic tool in the classification of myxoid soft tissue tumors
por: Sunitsch, Sandra, et al.
Publicado: (2018) -
MicroRNAs in Different Histologies of Soft Tissue Sarcoma: A Comprehensive Review
por: Smolle, Maria Anna, et al.
Publicado: (2017)