Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature

BACKGROUND: The blood‐brain barrier (BBB) is critical for cerebrovascular health. Although aging impairs the integrity of the BBB, the mechanisms behind this phenomenon are not clear. As mitochondrial components activate inflammation as mitochondria become dysfunctional, we examined how aging impact...

Descripción completa

Detalles Bibliográficos
Autores principales: Tyrrell, Daniel J., Blin, Muriel G., Song, Jianrui, Wood, Sherri C., Goldstein, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763766/
https://www.ncbi.nlm.nih.gov/pubmed/33225820
http://dx.doi.org/10.1161/JAHA.120.017820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763766/
https://www.ncbi.nlm.nih.gov/pubmed/33225820
http://dx.doi.org/10.1161/JAHA.120.017820

Ejemplares similares