Inward Rectifier K(+) Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM‐IbΔC‐X

BACKGROUND: Transgenic mice (TG) with heart‐directed overexpresion of the isoform of the transcription factor cyclic adenosine monophosphate response element modulator (CREM), CREM‐IbΔC‐X, display spontaneous atrial fibrillation (AF) and action potential prolongation. The remodeling of the underlyin...

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Detalles Bibliográficos
Autores principales: Pluteanu, Florentina, Seidl, Matthias D., Hamer, Sabine, Scholz, Beatrix, Müller, Frank U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763782/
https://www.ncbi.nlm.nih.gov/pubmed/33191843
http://dx.doi.org/10.1161/JAHA.119.016144

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