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Cytochrome P450 Expression and Chemical Metabolic Activity before Full Liver Development in Zebrafish

Zebrafish are used widely in biomedical, toxicological, and developmental research, but information on their xenobiotic metabolism is limited. Here, we characterized the expression of 14 xenobiotic cytochrome P450 (CYP) subtypes in whole embryos and larvae of zebrafish (4 to 144 h post-fertilization...

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Detalles Bibliográficos
Autores principales: Nawaji, Tasuku, Yamashita, Natsumi, Umeda, Haruka, Zhang, Shuangyi, Mizoguchi, Naohiro, Seki, Masanori, Kitazawa, Takio, Teraoka, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763843/
https://www.ncbi.nlm.nih.gov/pubmed/33322603
http://dx.doi.org/10.3390/ph13120456