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Putative Autoantigen Leiomodin-1 Is Expressed in the Human Brain and in the Membrane Fraction of Newly Formed Neurons

Nodding syndrome is a pediatric epilepsy disorder associated with Onchocerca volvulus infection, but the mechanism driving this relationship is unclear. One hypothesis proposes that parasite-induced immune responses cross-react with human leiomodin-1 resulting in immune-mediated central nervous syst...

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Detalles Bibliográficos
Autores principales: Nauen, David W., Haffner, Michael C., Kim, Juyun, Zheng, Qizhi, Yin, Hao, DeMarzo, Angelo M., Mahairaki, Vasiliki, Colantuoni, Carlo, Pickering, J. Geoffrey, Johnson, Tory P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763904/
https://www.ncbi.nlm.nih.gov/pubmed/33321732
http://dx.doi.org/10.3390/pathogens9121036