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Neurosteroids and Focal Epileptic Disorders

Neurosteroids are a family of compounds that are synthesized in principal excitatory neurons and glial cells, and derive from the transformation of cholesterol into pregnenolone. The most studied neurosteroids—allopregnanolone and allotetrahydrodeoxycorticosterone (THDOC)—are known to modulate GABA(...

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Detalles Bibliográficos
Autores principales: Lévesque, Maxime, Biagini, Giuseppe, Avoli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7763947/
https://www.ncbi.nlm.nih.gov/pubmed/33321734
http://dx.doi.org/10.3390/ijms21249391