RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-Small Cell Lung Cancer and IMR90 Lung Fibroblast Cell Lines

Phenanthriplatin is a new monofunctional platinum(II) complex that binds only one strand of DNA and acts by blocking gene transcription, but its effect on gene regulation has not been characterized relative to the traditional platinum-based complex, cisplatin. A549 non-small cell lung cancer and IMR...

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Detalles Bibliográficos
Autores principales: Monroe, Jerry D., Moolani, Satya A., Irihamye, Elvin N., Speed, Joshua S., Gibert, Yann, Smith, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764052/
https://www.ncbi.nlm.nih.gov/pubmed/33302475
http://dx.doi.org/10.3390/cells9122637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764052/
https://www.ncbi.nlm.nih.gov/pubmed/33302475
http://dx.doi.org/10.3390/cells9122637

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