Cargando…
RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-Small Cell Lung Cancer and IMR90 Lung Fibroblast Cell Lines
Phenanthriplatin is a new monofunctional platinum(II) complex that binds only one strand of DNA and acts by blocking gene transcription, but its effect on gene regulation has not been characterized relative to the traditional platinum-based complex, cisplatin. A549 non-small cell lung cancer and IMR...
Autores principales: | Monroe, Jerry D., Moolani, Satya A., Irihamye, Elvin N., Speed, Joshua S., Gibert, Yann, Smith, Michael E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764052/ https://www.ncbi.nlm.nih.gov/pubmed/33302475 http://dx.doi.org/10.3390/cells9122637 |
Ejemplares similares
-
Cisplatin and phenanthriplatin modulate long-noncoding RNA expression in A549 and IMR90 cells revealing regulation of microRNAs, Wnt/β-catenin and TGF-β signaling
por: Monroe, Jerry D., et al.
Publicado: (2021) -
Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations
por: Hucke, Anna, et al.
Publicado: (2018) -
Monofunctional Platinum(II) Anticancer Agents
por: Jin, Suxing, et al.
Publicado: (2021) -
Monofunctional and Interstrand DNA Adducts of Platinum(II)
Complexes
por: Brabec, Viktor, et al.
Publicado: (1994) -
The Chiral
Potential of Phenanthriplatin and Its Influence
on Guanine Binding
por: Johnstone, Timothy C., et al.
Publicado: (2014)