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Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus
The prolonged treatment of immunosuppressed (IS) individuals with anti-influenza monotherapies may lead to the emergence of drug-resistant variants. Herein, we evaluated oseltamivir and polymerase inhibitors combinations against influenza A/H3N2 infections in an IS mouse model. Mice were IS with cyc...
Autores principales: | Mhamdi, Zeineb, Fausther-Bovendo, Hugues, Uyar, Olus, Carbonneau, Julie, Venable, Marie-Christine, Abed, Yacine, Kobinger, Gary, Boivin, Guy, Baz, Mariana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764069/ https://www.ncbi.nlm.nih.gov/pubmed/33322333 http://dx.doi.org/10.3390/microorganisms8121968 |
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