Misincorporation of Galactose by Chondroitin Synthase of Escherichia coli K4: From Traces to Synthesis of Chondbiuronan, a Novel Chondroitin-Like Polysaccharide

Chondroitin synthase KfoC is a bifunctional enzyme which polymerizes the capsular chondroitin backbone of Escherichia coli K4, composed of repeated β3N-acetylgalactosamine (GalNAc)-β4-glucuronic acid (GlcA) units. Sugar donors UDP-GalNAc and UDP-GlcA are the natural precursors of bacterial chondroit...

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Detalles Bibliográficos
Autores principales: Leroux, Mélanie, Michaud, Julie, Bayma, Eric, Armand, Sylvie, Drouillard, Sophie, Priem, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764085/
https://www.ncbi.nlm.nih.gov/pubmed/33322778
http://dx.doi.org/10.3390/biom10121667

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