A Pyranoxanthone as a Potent Antimitotic and Sensitizer of Cancer Cells to Low Doses of Paclitaxel

Microtubule-targeting agents (MTAs) remain a gold standard for the treatment of several cancer types. By interfering with microtubules dynamic, MTAs induce a mitotic arrest followed by cell death. This antimitotic activity of MTAs is dependent on the spindle assembly checkpoint (SAC), which monitors...

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Detalles Bibliográficos
Autores principales: França, Fábio, Silva, Patrícia M. A., Soares, José X., Henriques, Ana C., Loureiro, Daniela R. P., Azevedo, Carlos M. G., Afonso, Carlos M. M., Bousbaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764177/
https://www.ncbi.nlm.nih.gov/pubmed/33322077
http://dx.doi.org/10.3390/molecules25245845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764177/
https://www.ncbi.nlm.nih.gov/pubmed/33322077
http://dx.doi.org/10.3390/molecules25245845

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