Cargando…
Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine
Due to their unique properties—the are biocompatible, easily accessible, and inexpensive with programmable properties—biopolymers are used in pharmaceutical and biomedical research, as well as in cosmetics and food. Collagen is one of the most-used biomaterials in biomedicine, being the most abundan...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764196/ https://www.ncbi.nlm.nih.gov/pubmed/33321865 http://dx.doi.org/10.3390/ma13245641 |
_version_ | 1783628199035404288 |
---|---|
author | Geanaliu-Nicolae, Ruxandra-Elena Andronescu, Ecaterina |
author_facet | Geanaliu-Nicolae, Ruxandra-Elena Andronescu, Ecaterina |
author_sort | Geanaliu-Nicolae, Ruxandra-Elena |
collection | PubMed |
description | Due to their unique properties—the are biocompatible, easily accessible, and inexpensive with programmable properties—biopolymers are used in pharmaceutical and biomedical research, as well as in cosmetics and food. Collagen is one of the most-used biomaterials in biomedicine, being the most abundant protein in animals with a triple helices structure, biocompatible, biomimetic, biodegradable, and hemostatic. Its disadvantages are its poor mechanical and thermal properties and enzymatic degradation. In order to solve this problem and to use its benefits, collagen can be used blended with other biomaterials such as alginate, chitosan, and cellulose. The purpose of this review article is to offer a brief paper with updated information on blended collagen-based formulations and their potential application in biomedicine. |
format | Online Article Text |
id | pubmed-7764196 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77641962020-12-27 Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine Geanaliu-Nicolae, Ruxandra-Elena Andronescu, Ecaterina Materials (Basel) Review Due to their unique properties—the are biocompatible, easily accessible, and inexpensive with programmable properties—biopolymers are used in pharmaceutical and biomedical research, as well as in cosmetics and food. Collagen is one of the most-used biomaterials in biomedicine, being the most abundant protein in animals with a triple helices structure, biocompatible, biomimetic, biodegradable, and hemostatic. Its disadvantages are its poor mechanical and thermal properties and enzymatic degradation. In order to solve this problem and to use its benefits, collagen can be used blended with other biomaterials such as alginate, chitosan, and cellulose. The purpose of this review article is to offer a brief paper with updated information on blended collagen-based formulations and their potential application in biomedicine. MDPI 2020-12-10 /pmc/articles/PMC7764196/ /pubmed/33321865 http://dx.doi.org/10.3390/ma13245641 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Geanaliu-Nicolae, Ruxandra-Elena Andronescu, Ecaterina Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine |
title | Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine |
title_full | Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine |
title_fullStr | Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine |
title_full_unstemmed | Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine |
title_short | Blended Natural Support Materials—Collagen Based Hydrogels Used in Biomedicine |
title_sort | blended natural support materials—collagen based hydrogels used in biomedicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764196/ https://www.ncbi.nlm.nih.gov/pubmed/33321865 http://dx.doi.org/10.3390/ma13245641 |
work_keys_str_mv | AT geanaliunicolaeruxandraelena blendednaturalsupportmaterialscollagenbasedhydrogelsusedinbiomedicine AT andronescuecaterina blendednaturalsupportmaterialscollagenbasedhydrogelsusedinbiomedicine |